pISSN 2671-8790 eISSN 2671-8804

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J Korean Soc Transplant 2014; 28(1): 25-35

Published online March 31, 2014

https://doi.org/10.4285/jkstn.2014.28.1.25

© The Korean Society for Transplantation

Analysis of 1,500 Kidney Transplantations at Sungkyunkwan University

Jae Woong Hong, M.D., Milljae Shin, M.D., Hyung Hwan Moon, M.D., Sanghoon Lee, M.D., Jong Man Kim, M.D., Jae Berm Park, M.D., Choon Hyuck David Kwon, M.D., Jae-Won Joh, M.D., Suk-Koo Lee, M.D. and Sung-Joo Kim, M.D.

Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea

Correspondence to: 김성주, 서울시 강남구 일원로 81 성균관대학교 의과대학 삼성서울병원 외과학교실, 135-710
Tel: 02-3410-3476, Fax: 02-3410-0040
E-mail: kmhyj111@gmail.com

Received: October 23, 2013; Revised: November 7, 2013; Accepted: January 16, 2014

Abstract

Background: The most effective treatment for end-stage renal disease is kidney transplantation, and the number of kidney transplantations has shown a rapid increase. The aim of this study was to determine graft survival and functional outcome of 1,500 kidney transplant cases in a single center. We also investigated the factors affecting graft failure after kidney transplantation.
Methods: We retrospectively reviewed the clinical data of 1,500 pairs of donors and subsequent recipients who underwent kidney transplantation in Samsung Medical Center, from February 1995 to January 2012.
Results: The mean follow-up period was 2,241.5±1,609.4 days. There were 851 (56.7%) male recipients; 62 (4.1%) recipients were younger than 19 years old. Eleven (0.7%) cases were ABO blood group incompatible kidney transplant. A total of 531 (35%) deceased and 969 (65%) living donors were included. Among them, 191 (12.7%) recipients were experienced in graft failure. The most common cause of graft loss was chronic allograft nephropathy. One-year, 5-year, 10-year, and 15-year graft survival were 97.3%, 92.8%, 81.6%, and 75.1% (85.2% for living, 75.4% for deceased donor), respectively. Higher incidence of graft failure was observed in recipients who received deceased donor kidneys or experienced a rejection episode.
Conclusions: In our experience, overall 10-year graft survival after kidney transplantation was 81.6%. This report demonstrated that the type of donor (living or deceased) and history of allograft rejection are the only significant factors affecting graft survival.

Keywords: Kidney transplantation, Living donors, Deceased donor, Graft survival