Table. 3.

Risk factors associated with patient death

Risk factor Univariate analysis Multivariate analysis


HR (95% CI) P-value HR (95% CI) P-value
Recipient
Age 1.08 (1.05–1.11) <0.001 1.07 (1.04–1.10) <0.001
Sex 1.05 (0.65–1.70) 0.841 - -
BMI 1.05 (0.98–1.12) 0.196 - -
DM 2.22 (1.30–3.79) 0.004 1.18 (0.67–2.09) 0.565
HTN 0.85 (0.47–1.53) 0.578 - -
Donor
Age 1.03 (1.01–1.05) 0.009 1.02 (0.99–1.04) 0.195
Sex 1.07 (0.66–1.72) 0.784 - -
BMI 1.01 (0.94–1.09) 0.836 - -
DM 1.68 (0.13–21.48) 0.689 - -
HTN 3.81 (1.63–8.90) 0.002 2.51 (1.02–6.17) 0.046
sCr 0.69 (0.16–3.08) 0.629 - -
History of KT 1.19 (0.37–3.80) 0.766 1.68 (0.51–5.56) 0.396
ABO incompatible 0.76 (0.18–3.17) 0.708 - -
Inductive agent
r-ATG vs. no agent 1.14 (0.55–2.36) >0.999 - -
Basiliximab vs. no agent 0.91 (0.50–1.67) >0.999 - -
r-ATG vs. basiliximab 1.25 (0.59–2.67) >0.999 - -
No. of HLA I mismatches 1.14 (0.68–1.90) 0.628 - -
No. of HLA II mismatches 2.46 (1.44–4.19) <0.001 1.97 (1.14–3.42) 0.016
DSA(+) 0.80 (0.20–3.32) 0.763 - -
Total operation time 1.00 (1.00–1.00) 0.529 - -
Cold ischemic time 1.00 (1.00–1.00) 0.487 - -
Anastomosis time 1.00 (1.00–1.00) 0.219 - -

HR, hazard ratio; CI, confidence interval; BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; sCr, serum creatinine; KT, kidney transplantation; r-ATG, rabbit anti-thymocyte antigen; HLA, human leukocyte antigen; DSA, donor-specific antibody.

Korean J Transplant 2022;36:173~179 https://doi.org/10.4285/kjt.22.0018
© Korean Journal of Transplantation