Table. 1.

Demographic and clinical characteristics of patients in the adult LDLT, adult DDLT, and pediatric LT groups

Variable Adult LDLT Adult DDLT Pediatric LT P-value (adult LDLT vs. DDLT)
No. of patients 207 22 22
Recipient (male:female) 169:38 15:7 7:15 0.741
Recipient age (yr) 46.2±8.3 44.4±9.9 2.2±3.2 0.236
Primary disease 0.483a)
HBV-LC 177 (85.5) 20 (90.9)
ALF 14 (6.8) 3 (13.6)
HCV-LC 6 (2.9)
ALD 4 (1.9)
Cryptogenic LC 2 (1.0) 1 (4.5)
Wilson disease 2 (1.0)
PSC 1 (0.5) 1 (4.5)
SBC 1 (0.5)
BA 16 (72.7)
Metabolic disease 3 (13.6)
Preoperative laboratory finding
Total bilirubin (mg/dL) 10.6±13.8 7.4±7.6 15.4±14.7 0.276
Serum creatinine (mg/dL) 1.09±0.91 0.91±0.21 0.61±0.97 0.351
Prothrombin time (INR) 2.39±1.32 2.03±0.78 1.51±0.45 0.223
Platelet count (×103/mL) 61.8±44.1 44.1±27.7 160.7±81.3 0.067
MELD/PELD score 25.5±10.8 24.6±9.6 12.1±4.7 0.693
HCC at explant liver 48 (23.2) 3 (13.6) 0 0.569
Donor sex (male:female) 171:36b) 15:7 8:14 0.099
Donor age (yr) 27.1±7.3 23.4±10.4 30.7±5.2 0.036
Graft type (n)
Whole liver 21 (95.5) 1 (4.5)
Right liver 158 (76.3) 1 (4.5)
Left liver 29 (14.0) 12 (54.5)
Left lateral section 9 (40.9)
Dual-graft 20 (9.7)
Graft weight (g) 669.3±148.1 1215.3±271.6 272.5±83.1 <0.001
Graft-recipient weight ratio 1.01±0.25 1.76±0.34 2.61±0.65 <0.001
Ischemic time (min)
Cold 75.5±86.4 352.6±208.9 27.1±24.7 <0.001
Warm 52.1±110.5 138.6±128.8 31.2±13.6 <0.001

Values are presented as mean±standard deviation or number (%).

LDLT, living donor liver transplantation; DDLT, deceased donor liver transplantation; HBV, hepatitis B virus; LC, liver cirrhosis; ALF, acute liver failure; HCV, hepatitis C virus; ALD, alcoholic liver disease; PSC, primary sclerosing cholangitis; SBC, secondary biliary cirrhosis; BA, biliary atresia; INR, international normalized ratio; MELD, model for end-stage liver disease; PELD, pediatric end-stage liver disease; HCC, hepatocellular carcinoma.

a)Comparison between HBV-LC and other groups; b)Including 20 cases of dual-graft donors.

Korean J Transplant 2022;36:45~53 https://doi.org/10.4285/kjt.21.0031
© Korean Journal of Transplantation