Table. 1.

Characteristics of older and younger living donors and recipient

Variable Younger donora) (n=826) Older donorb) (n=33) P-value
Donor
Age (yr) 39.4 62.6 <0.001
Female 398 (48.2) 15 (45.5) 0.753
BMI (kg/m2) 24.10 24.26 0.620
Underlying disease
DM 5 (0.61) 0 >0.999
HTN 24 (2.75) 2 (6.06) 0.244
Creatinine level (mg/dL) 0.85 0.85 0.835
Recipient
Age (yr) 42.4 46.2 0.138
Female 356 (43.1) 16 (48.5) 0.540
BMI (kg/m2) 22.53 22.97 0.411
Dialysis duration (day) 697.58 579.73 0.440
Number of HLA mismatches 2.73 3.00 0.381
Risk factor
DM 134 (16.22) 5 (15.15) 0.870
HTN 679 (82.20) 26 (78.79) 0.616
Underlying kidney disease 0.610
DM nephropathy 116 (14.04) 5 (15.15) -
GN (IgA, FSGS, Other GN) 239 (28.93) 9 (27.27) -
ADPCK 33 (4.00) 3 (9.09) -
Hypertensive 118 (14.29) 5 (15.15) -
Other and unknown 320 (38.74) 11 (33.33) -
DSA-positivec) 27 (3.43) 1 (3.45) >0.999
Induction method 0.148
No agent 380 (46.0) 10 (30.3) -
Basiliximab 368 (44.55) 18 (54.55) -
r-ATG 43 (5.21) 2 (6.06) -
r-ATG+rituximab 35 (4.2) 3 (9.09) -
Maintenance regimen 0.441
CsA+MMF+PD 340 (41.2) 10 (30.3) -
FK+MMF+PD 469 (56.8) 23 (69.7) -
Sirolimus or everolimus Combination 14 (1.69) 0 -
Otherd) 3 (0.36) 0 -
Follow-up duration (yr) 11.19 8.99 0.002

Values are presented as number (%).

BMI, body mass index; DM, diabetes mellitus; HTN, hypertension; HLA, human leukocyte antigen; GN, glomerulonephritis; IgA, immunoglobulin A; FSGS, focal segmental glomerulosclerosis; ADPCK, autosomal dominant polycystic kidney disease; DSA, donor-specific anti-HLA antibodies; r-ATG, rabbit anti-thymocyte globulin; CsA, cyclosporin A; MMF, mycophenolate mofetil; PD, prednisone; FK, tacrolimus.

a)Living donor age 18–59 group; b)Living donor age ≥60 group; c)39 From younger donor and 4 from older donor was not included due to unknown result; d)Other maintenance regimen refers to FK+mizoribine+PD.

Korean J Transplant 2021;35:238~246 https://doi.org/10.4285/kjt.21.0020
© Korean Journal of Transplantation