Definitions of terms in the process of controlled DCD
1. No flow time: time from cardiac arrest to start of cardiopulmonary resuscitation
2. Total warm ischemic timeUncontrolled: from the time of the cardiac arrest to the start of preservation for sustaining organ function. Within a maximum of 150 minutesControlled: from the time of WLST to the start of perfusion (withdrawal period+asystolic warm period)
3. Withdrawal period, agonal period: from the time of WLST to asystole
4. Functional (true) warm ischemic period :after the implementation of WLST, from the time that one of the two conditions below is met to asystole.(1) systolic blood pressure <50 mmHg(2) peripheral oxygen saturation <70%
5. Asystole: under invasive arterial blood pressure monitoring, the time that the pulse wave was lost. If invasive arterial blood pressure monitoring is unavailable, the first time that the heart rate shows “zero” on an electrocardiogram can be used.
6. No touch timea): from asystole, the time to observe self-resuscitation of the heart without any treatment for 5 minutes
7. Asystolic warm period, primary warm ischemic time: time from asystole to the start of perfusion
8. Declaration of death: take 5 minutes of no touch time after asystole. Then, a declaration of death can be made.
9. Preservation time9. Preservation time: from the time when preservation was started to sustain organ function until organ procurement.
DCD, donation after circulatory death; WLST, withdrawal of life-sustaining treatment.
a)“Five minutes of no touch time” is consented unanimously by Korean DCD research group members.