pISSN 2671-8790 eISSN 2671-8804

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Case Report

Korean J Transplant 2019; 33(3): 60-64

Published online September 30, 2019

https://doi.org/10.4285/jkstn.2019.33.3.60

© The Korean Society for Transplantation

Kidney transplantation in human immunodeficiency virus-infected patients: a report of two cases and a review of the literatures

Hong Pil Hwang1, Hee Chul Yu1, Kyung Pyo Kang2, Won Kim2, Sung Kwang Park2, Jeong Sang Ku2, Hyeongwan Kim2, Sik Lee2

1Department of General Surgery and 2Department of Internal Medicine, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital, Chonbuk National University Medical School, Jeonju, Korea

Correspondence to: Sik Lee
Department of Internal Medicine, Chonbuk National University Medical School, 567 Baekje-daero, Deokjin-gu, Jeonju 54896, Korea
Tel: +82-63-250-2151, Fax: +82-63-254-1609 E-mail: kidney@jbnu.ac.kr

Received: March 1, 2019; Revised: July 15, 2019; Accepted: July 15, 2019

This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Human immunodeficiency virus (HIV) infection was traditionally considered an absolute contraindication for transplantation because of concerns about HIV disease progression due to immunosuppression. Since potent antiretroviral therapies (ARTs) have become widely available, the prognosis of HIV-infected kidney transplant recipients has dramatically improved. Recent results of prospective multicenter trials on kidney transplantation (KT) in HIV-positive candidates have demonstrated the success and challenges of transplantation in this population. Several studies have reported comparable patient and graft outcomes between HIV-infected and HIV-uninfected recipients after KT in the era of potent combined ARTs. We report two cases of HIV-infected patients who underwent KT at our hospital. In this paper, we present a detailed report of two cases and provide a short review of the existing literature.

Keywords: Human immunodeficiency virus, Kidney transplantation